Best Supplements for Reduced Salivary Levels of Mutans Streptococci
Ranked by research evidence. Compare 11 supplements across 14 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence4 studies
Across 4 randomized controlled trials, all 4 reported beneficial effects of *Lactobacillus paracasei* VPro 224 (specifically strain SD1 in most studies) on reducing salivary levels of mutans streptococci, with effect sizes ranging from moderate to large. The most commonly studied population was children (including preschool children), with sample sizes ranging from 40 to 124. Study durations were not consistently reported, precluding a median duration estimate.
11 supplements
- ModerateLactobacillus paracasei VPro 224Across 4 randomized controlled trials, all 4 reported beneficial effects of *Lactobacillus paracasei* VPro 224 (specifically strain SD1 in most studies) on reducing salivary levels of mutans streptococci, with effect sizes ranging from moderate to large. The most commonly studied population was children (including preschool children), with sample sizes ranging from 40 to 124. Study durations were not consistently reported, precluding a median duration estimate.4 beneficial4 studies