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Evidence-Based Supplement Research
Evidence-Based Supplement Research

African Mango

What does the research say about African Mango?

3 health outcomes synthesised

Research on African mango (Irvingia gabonensis) seed extract has investigated its effects on three health outcomes, primarily in overweight and obese adults. The strongest evidence, supported by three studies with moderate strength, is for reductions in waist circumference and body weight, with effect sizes ranging from small to large. The most studied dose is 150 mg twice daily, though dose reporting is generally limited.

Strongest evidence: Moderate evidence supports African mango seed extract for reducing waist circumference (3 of 3 studies show small beneficial effects), body weight (3 of 3 studies, mixed small-to-large effects), and triglyceride levels (3 of 3 studies show small effects). The median study duration is around 90 days, and the studied populations are primarily overweight and obese adults, including those with metabolic syndrome.

Effective dose patterns: Only one study reported a specific dose for waist circumference and triglycerides: 150 mg twice daily. No standardized dose data were available for body weight. Doses across outcomes converge around 300 mg/day (150 mg twice daily), but this is based on limited evidence.

Population insights: All evidence comes from overweight and obese adults, with some studies also including individuals with metabolic syndrome. No data were found for normal-weight individuals or other populations, so generalizability is unknown.

Notable caveats: The evidence base is small (only 3 studies per outcome), so conclusions are preliminary. The literature is subject to publication bias — null-result studies are less likely to be published. Dose-response data are lacking, and effect sizes varied (small to large) for body weight, indicating inconsistency in the magnitude of benefit.

Frequently asked

  • What is African Mango good for according to research?
    Current research, based on three studies per outcome, suggests African mango seed extract may help reduce waist circumference, body weight, and triglyceride levels. All three outcomes show moderate evidence strength, with all studies reporting beneficial effects, though effect sizes vary.
  • What dose of African Mango is typically used in studies?
    One study used 150 mg twice daily for reducing waist circumference and triglycerides. No standardized dose was reported for body weight. Overall, dose reporting is limited, and the evidence base is too small to establish a reliable effective dose range.
  • Who benefits most from African Mango?
    The research primarily involves overweight and obese adults, including those with metabolic syndrome. Effects on waist circumference and body weight were noted at around 90 days. There is no evidence for normal-weight individuals or other populations.
  • Are there caveats or limitations in the research on African Mango?
    Yes. The evidence base is small (only 3 studies per outcome), so findings are preliminary. Publication bias is likely, as null results are less published. Dose-response data are absent, and effect sizes for body weight were inconsistent (small to large), suggesting variability in benefit.
  • Does African Mango help with reducing triglyceride levels?
    Three studies report small beneficial effects on triglycerides, with two reaching statistical significance. Evidence comes from a meta-analysis, an RCT (150 mg twice daily for 90 days), and a systematic review. However, the evidence is still moderate and preliminary due to the small number of studies.

Safety profile

3 studies reporting safety data

Across 3 clinical studies reporting safety data on African Mango, no specific adverse events were found to be significantly increased compared to control. The supplement was generally described as well tolerated in multiple studies, with reported adverse events such as headache and sleep difficulty being minor and unquantified. No serious adverse events were flagged in any of the studies.

Caveats: Evidence is limited to short-term studies (most ≤12 weeks); long-term safety not established. The evidence base is small (3 studies), and studies were likely powered for efficacy rather than safety, so rare adverse events may not be detected.

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