Aloe and Reduced Acne Erythema

• Efficacy and Safety of a Dual-Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split-Face Randomized Controlled Trial.

  • 2026-05-01
  • RCT
  • Journal of cosmetic dermatology 25(5)
  • • Suphagan Boonpethkaew
    • Pimsiri Anansiripun
    • Warittha Maitrisathit
    • Yanisa Ratanapokasatit
    • Sonphet Chirasuthat
    • Panrudee Wechsuruk
    • Penpun Wattanakrai

  • PubMed: 42087432
  • DOI: 10.1111/jocd.70894

  1 Insight on

  • Reduced Acne Erythema

  • High evidence
  • Clinical

  Both treatment modalities significantly reduced AE. The laser-treated side demonstrated a faster clinical response, with a significant reduction compared to baseline at 2 weeks, whereas AV gel required 4 weeks to achieve a comparable effect (within-group p < 0.05; no between-group difference). At the 8-week follow-up, the response rate was 72% for the laser-treated sides and 69% for the AV-treated sides.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes