Beetroot and Reduced Diastolic Blood Pressure

• Plasma nitrate, dietary nitrate, blood pressure, and vascular health biomarkers: a GRADE-Assessed systematic review and dose-response meta-analysis of randomized controlled trials.

  • 2025-03-24
  • Meta-Analysis · n = 1,823
  • Nutrition journal 24(1)
  • • Mostafa Norouzzadeh
    • Minoo Hasan Rashedi
    • Shadi Ghaemi
    • Niloufar Saber
    • Artemiss Mirdar Harijani
    • Hamzeh Habibi
    • Soroush Mostafavi
    • Fatemeh Sarv
    • Hossein Farhadnejad
    • Farshad Teymoori
    • Mohsen Khaleghian
    • Parvin Mirmiran

  • PubMed: 40128734
  • DOI: 10.1186/s12937-025-01114-8

  5 Insights on

  • Reduced Diastolic Blood Pressure

  • High evidence
  • Clinical

  a decrease in diastolic BP for each mmol increase in NO3 intake (WMD: -0.12 mmHg; 95% CI: -0.21, -0.03) was shown.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  per mmol increase in administered dose

• Inter-individual differences in the blood pressure lowering effects of dietary nitrate: a randomised double-blind placebo-controlled replicate crossover trial.

  • 2025-02-24
  • RCT
  • European journal of nutrition 64(2)
  • • Eleanor Hayes
    • Shatha Alhulaefi
    • Mario Siervo
    • Eleanor Whyte
    • Rachel Kimble
    • Jamie Matu
    • Alex Griffiths
    • Marc Sim
    • Mia Burleigh
    • Chris Easton
    • Lorenzo Lolli
    • Greg Atkinson
    • John C Mathers
    • Oliver M Shannon

  • PubMed: 39992469
  • DOI: 10.1007/s00394-025-03616-x

  2 Insights on

  • Reduced Diastolic Blood Pressure

  • High evidence
  • Rigorous Journal
  • Adults

  Nitrate-rich beetroot juice supplementation elevated plasma nitrate and nitrite concentrations and reduced systolic (mean:-7mmHg, 95%CI: -3 to -11mmHg) and diastolic (mean:-6mmHg, 95%CI: -2 to -9mmHg) BP versus placebo.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  140 ml nitrate-rich beetroot juice (~14.0 mmol nitrate)