Berberine and Developed Polymorphic Ventricular Tachycardia

• Cardiovascular toxicity associated with supplement use.

  • 2025-09-17
  • Review
  • Clinical toxicology (Philadelphia, Pa.) 63(11)
  • • Justin Corcoran

  • PubMed: 40960841
  • DOI: 10.1080/15563650.2025.2550983

  5 Insights on

  • Developed Polymorphic Ventricular Tachycardia

  • Low evidence

  Inhibition of cardiac myocyte voltage-gated potassium channels is associated with berberine, leading to prolongation of the QT interval and polymorphic ventricular tachycardia.

  Effect

  Harmful

  Effect size

  Small

  Significant

  Yes