Berberine and Improved Fasting Plasma Glucose

• Probiotics, synbiotics and berberine in Type 2 diabetes mellitus: A systematic review, meta-analysis, and molecular dynamics simulation study.

  • 2026-05-29
  • Meta-Analysis
  • PloS one 21(5)
  • • Md Shadin
    • Md Shimul Bhuia
    • Mohammed Alfaifi
    • Faisal H Altemani
    • Abdullah H Altemani
    • Faisal Alsenani
    • Na'il Saleh
    • Muhammad Torequl Islam

  • PubMed: 42213651
  • DOI: 10.1371/journal.pone.0348907

  2 Insights on

  • Improved Fasting Plasma Glucose

  • High evidence
  • Clinical

  The pooled analysis showed significant but modest reductions in FPG (-0.71 mmol·L⁻¹) and HbA1c (-0.19%)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Efficacy and safety of berberine on the components of metabolic syndrome: a systematic review and meta-analysis of randomized placebo-controlled trials.

  • 2025-07-16
  • Systematic Review
  • Frontiers in pharmacology 16
  • • Dangzhen Liu
    • Haiyan Zhao
    • Yiwen Zhang
    • Jingqing Hu
    • Hong Xu

  • PubMed: 40740996
  • DOI: 10.3389/fphar.2025.1572197

  10 Insights on

  • Improved Fasting Plasma Glucose

  • High evidence

  berberine significantly reduces ... fasting plasma glucose (FPG) (WMD: -0.515 mmol/L; 95% CI: -0.847 to -0.183; p = 0.002)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  not stated in the abstract