Berberine and Reduced Liver Fat Content

• Berberine and Adiposity in Diabetes-Free Individuals With Obesity and MASLD: A Randomized Clinical Trial.

  • 2026-01-02
  • RCT
  • JAMA network open 9(1)
  • • Lubi Lei
    • Bin Wang
    • Lingshan Zhao
    • Jingkuo Li
    • Xiaofang Yan
    • Jiandong Jiang
    • Lulu Wang
    • Gang Ren
    • Yinchu Li
    • Xiaoguang Cheng
    • Xiaoyan Yan
    • Yidan Zhu
    • Yuanlin Guo
    • Hui Zhong
    • Haibo Zhang
    • Jing Li

  • PubMed: 41543854
  • DOI: 10.1001/jamanetworkopen.2025.54152

  5 Insights on

  • Reduced Liver Fat Content

  • High evidence
  • Rigorous Journal
  • Clinical

  No significant differences were observed between study arms for ... liver fat content (0.9% [97.5% CI, -0.4% to 2.1%])

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  1 g/d