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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Cocoa and Reduced Diastolic Blood Pressure

Doses used in studies

mg/day: 1,000 (median 1,000, IQR 1,000–1,000) — 1 study

Time to effect

Median: 4.3 weeks · IQR 4.3 weeks–4.3 weeks · Range 4.3 weeks–4.3 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

The Effect of Antioxidant Polyphenol Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis.
- 2024-12-05
- Meta-Analysis · n = 126
- Nutrients 16(23)
- - Sitong Wan
  - Junjie Luo
  - Yinhua Zhu
  - Peng An
  - Yongting Luo
  - Qingchang Xing
- PubMed: 39683599
- DOI: 10.3390/nu16234206
3 Insights on
- Reduced Diastolic Blood Pressure
- High evidence
- Rigorous Journal
catechin supplementation decreased systolic (-1.56 [-2.75, -0.37] mmHg) and diastolic blood pressure (-0.95 [-1.69, -0.20] mmHg)
Effect
Beneficial
Effect size
Small
Significant
Yes
Cocoa flavanols improve peakVO2 and exercise capacity in a randomized double blinded clinical trial in healthy elderly people.
- 2023
- RCT
- Food & function 14(16)
- - Michael Gröne
  - Dragos Andrei Duse
  - Nicolas Kramser
  - Niklas Ophoff
  - Hendrik Schweers
  - Fabian Voß
  - Christine Quast
  - Roberto Sansone
  - Christian Heiss
  - Christian Jung
  - Malte Kelm
  - Ralf Erkens
- PubMed: 37526943
- DOI: 10.1039/d3fo01737k
7 Insights on
- Reduced Diastolic Blood Pressure
- High evidence
- Rigorous Journal
- Mixed
CF decreased resting systolic and diastolic BP by 5.4 mmHg (95% CI -10.7 to -0.1 mmHg) and 2.9 mmHg (95% CI -5.5 to -0.4 mmHg), respectively.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
500 mg twice daily