Cocoa flavanols protect cognitive function, cerebral oxygenation, and mental fatigue during severe hypoxia.
- 2023-08-01
- RCT · n = 12
- Journal of applied physiology (Bethesda, Md. : 1985) 135(2)
- Peter M Bloomfield
- James P Fisher
- David M Shaw
- Nicholas Gant
- PubMed: 37471213
- DOI: 10.1152/japplphysiol.00219.2023
- High evidence
Subjective fatigue was increased by 900% with placebo compared with flavanols during poikilocapnic hypoxia (effect of flavanols, P = 0.004).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 15 mg/kg body weight