Moringa and Increased CD4+ T Cell Count

• A double-blind, randomized controlled trial to examine the effect of Moringa oleifera leaf powder supplementation on the immune status and anthropometric parameters of adult HIV patients on antiretroviral therapy in a resource-limited setting.

  • 2021-12-31
  • RCT
  • PloS one 16(12)
  • • Aisha Gambo
    • Indres Moodley
    • Musa Babashani
    • Tesleem K Babalola
    • Nceba Gqaleni

  • PubMed: 34972169
  • DOI: 10.1371/journal.pone.0261935

  4 Insights on

  • Increased CD4+ T Cell Count

  • High evidence
  • Clinical

  the treatment by time interaction shows a significant difference in CD4 counts by treatment group (p<0.0001). A further estimate of fixed effects showed that the CD4 counts among MOG were 10.33 folds greater than COG over the study period.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

  Dose

  not specified

• Effects of Moringa oleifera supplementation on immune and nutritional biomarkers in adults living with HIV: a systematic review and meta-analysis.

  • 2025-09-08
  • Systematic Review
  • Frontiers in nutrition 12
  • • Dachuan Jin
    • Shunqin Jin
    • Tao Zhou
    • Guoping Sheng
    • Peng Gao
    • Guangming Li

  • PubMed: 40989801
  • DOI: 10.3389/fnut.2025.1667158

  4 Insights on

  • Increased CD4+ T Cell Count

  • High evidence
  • Clinical

  MO supplementation significantly increased CD4+ T cell count [standardized mean differences (SMD) = 1.4, 95% CI 0.59-2.20, p < 0.001]

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes