Efficacy and safety of plant-derived bioactive compounds in the treatment of psoriasis vulgaris: a systematic review and network meta-analysis.
- 2026-06-22
- Systematic Review · n = 544
- Frontiers in medicine 13
- Yue Du
- Shouxu Zhang
- Tian Lv
- Xiaoxuan Chen
- Lingling Yuan
- Haomin Zhang
- Guangshan Chen
- Weiling Chen
- Lingling Li
- PubMed: 42440434
- DOI: 10.3389/fmed.2026.1844822
- High evidence
- Clinical
Most combination therapies significantly outperformed monotherapy in PASI reduction. TG combined with topical therapy (TOP) produced the greatest reduction in PASI scores [mean difference (MD) = -13.96, 95% confidence interval (CI) (-16.88, -11.03)], with the highest surface under the cumulative ranking curve (SUCRA) value of 99.80%.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes