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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Perilla and Increased Bone Mineral Density

Doses used in studies

ml/day: 7 (median 7, IQR 7–7) — 1 study

Time to effect

Median: 12.2 months · IQR 12.2 months–12.2 months · Range 12.2 months–12.2 months — Reported in 1 of 1 study

1 of 1 paper

Perilla seed oil improves bone health by inhibiting bone resorption in healthy Japanese adults: A 12-month, randomized, double-blind, placebo-controlled trial.
- 2023-01-13
- RCT · n = 52
- Phytotherapy research : PTR 37(6)
- - Kentaro Matsuzaki
  - Shahdat Hossain
  - Harumi Wakatsuki
  - Yoko Tanabe
  - Miho Ohno
  - Setsushi Kato
  - Osamu Shido
  - Michio Hashimoto
- PubMed: 36637040
- DOI: 10.1002/ptr.7728
3 Insights on
- Increased Bone Mineral Density
- High evidence
- Adults
Compared with the placebo group, %YAM levels increased and serum TRACP-5b levels decreased significantly in the PO group at 12-month
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
7.0 ml/day