Pine and Reduced Hospital Admission Rate

Safety in these studies

Overall tolerabilityReported
Because of its favorable safety profile and sustained anti-inflammatory action, Pycnogenol represents an option as an add-on supplement for OA patients.
from: Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine
gastric complicationsReported
Sparing the use of nonsteroidal anti-inflammatory drugs, supplementation with the pine bark extract reduced gastric complications and hospital admissions of OA patients.
from: Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine

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Review on Sustained Relief of Osteoarthritis Symptoms with a Proprietary Extract from Pine Bark, Pycnogenol.