Polypodium Leucotomos and Reduced Cyclobutane Pyrimidine Dimer Level

• Oral Polypodium leucotomos extract decreases ultraviolet-induced damage of human skin.

  • 2004-12
  • Clinical Trial
  • Journal of the American Academy of Dermatology 51(6)
  • • Maritza A Middelkamp-Hup
    • Madhu A Pathak
    • Concepcion Parrado
    • David Goukassian
    • Francisca Rius-Díaz
    • Martín C Mihm
    • Thomas B Fitzpatrick
    • Salvador González

  • PubMed: 15583582
  • DOI: 10.1016/j.jaad.2004.06.027

  6 Insights on

  • Reduced Cyclobutane Pyrimidine Dimer Level

  • Moderate evidence

  less cyclobutane pyrimidine dimers (P < .001)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  7.5 mg/kg