Isoflavones and changes in body weight and severe hot flashes in postmenopausal women: A secondary analysis of a randomized clinical trial.
- 2025-07-05
- RCT · n = 84
- Maturitas 200
- Hana Kahleova
- Tatiana Znayenko-Miller
- Richard Holubkov
- Neal D Barnard
- PubMed: 40663878
- DOI: 10.1016/j.maturitas.2025.108661
- High evidence
- Clinical
Mean body weight decreased by 3.6 kg in the vegan group and by 0.2 kg in the control group (effect size: -3.4 kg [95% CI -4.5 to -2.3], p < 0.001). ... The increased consumption of each of the three isoflavones was associated with weight loss (r = -0.67, p < 0.001 for genistein; ...)
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes