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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Quercetin and Reduced Acute Mountain Sickness Incidence

Doses used in studies

mg/day: 500 (median 500, IQR 500–500) — 1 study

Time to effect

Median: 2.1 weeks · IQR 2.1 weeks–2.1 weeks · Range 2.1 weeks–2.1 weeks — Reported in 1 of 1 study

1 of 1 paper

Quercetin prophylaxis in prevention of acute mountain sickness (AMS): a randomized, double blind, placebo controlled phase-II clinical trials.
- 2026-07-11
- RCT · n = 55
- European journal of nutrition 65(5)
- - Sarada S K Sagi
  - Vandana Kirar
  - Jyotsna Prasad
  - Somnath Singh
  - Vaishnavi Rathi
  - Khudsia Sultana
  - Vijay Kumar Singh
  - Saroj Kumar Verma
  - Dharmendra Kumar
  - Vinod Kumar
  - Shiva Saxena
  - Rajeev Mishra
  - Vishwendra Vikram Singh
  - Sneha Chopra
  - Rajeev Varshney
- PubMed: 42435069
- DOI: 10.1007/s00394-026-04059-8
6 Insights on
- Reduced Acute Mountain Sickness Incidence
- High evidence
- Rigorous Journal
- Adults
AMS prevalence was 2% in the quercetin group versus 25% in the placebo group.
Effect
Beneficial
Effect size
Large
Significant
Yes
Dose
500 mg/day