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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Quercetin

Safety profile

3 studies reporting safety data2 increased-risk findings

Across three clinical studies, quercetin supplementation was associated with increased risk of sleep disturbances and anxiety in one small study (4/6 vs 0/6 in the quercetin plus placebo arm). In the same study, overall non-serious adverse events were more frequent in the quercetin group (65 vs 22), though no serious adverse events were reported. Two other studies found no significant differences in adverse effects, including postoperative nausea and vomiting, and described quercetin as well tolerated with high adherence.

Caveats: Evidence is limited to small, short-term studies; the finding of increased anxiety and sleep disturbances comes from a single trial with only 6 participants per arm. Studies were designed for efficacy endpoints, not safety, and rare adverse events may go undetected.

Most-studied combinations with Quercetin

most supplement research is combination research
Also studied with:Vitamin E (2), Vitamin C (2)
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