Resveratrol and Improved Insulin Sensitivity

• Clinical Efficacy of Curcumin, Resveratrol, Silymarin, and Berberine on Cardio-Metabolic Risk Factors Among Patients With Type 2 Diabetes Mellitus: A Systemic Review and Bayesian Network Meta-Analysis.

  • 2025-05-29
  • Systematic Review · n = 337
  • Phytotherapy research : PTR 39(12)
  • • Runyu Miao
    • Boxun Zhang
    • Danni Zhou
    • Mengjiao Kang
    • Jiaxing Tian
    • Linhua Zhao
    • Xiaolin Tong

  • PubMed: 40439602
  • DOI: 10.1002/ptr.8431

  12 Insights on

  • Improved Insulin Sensitivity

  • High evidence
  • Clinical

  silymarin significantly improved fasting plasma glucose (FPG), HOMA-IR, and hemoglobin A1c (HbA1c) (P < 0.05)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Polyphenol Intervention Ameliorates Non-Alcoholic Fatty Liver Disease: An Updated Comprehensive Systematic Review.

  • 2024-11-29
  • Systematic Review
  • Nutrients 16(23)
  • • Yazan Ranneh
    • Alaa S Bedir
    • Abdelghafar M Abu-Elsaoud
    • Seham Al Raish

  • PubMed: 39683546
  • DOI: 10.3390/nu16234150

  8 Insights on

  • Improved Insulin Sensitivity

  • High evidence
  • Rigorous Journal
  • Clinical

  resveratrol did not present consistent results across all the studies

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• The Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review.

  • 2026-05-26
  • Systematic Review
  • Molecules (Basel, Switzerland) 31(11)
  • • Patrycja Gazda
    • Paweł Glibowski

  • PubMed: 42280140
  • DOI: 10.3390/molecules31111837

  13 Insights on

  • Improved Insulin Sensitivity

  • High evidence

  Resveratrol showed mixed but potentially beneficial effects on insulin sensitivity ... although the clinical outcomes remained inconsistent across studies.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  not stated