Across 3 studies, 2 reported beneficial effects (small to moderate) on reducing inflammation, while the highest-quality RCT found no significant benefit. The predominant effect size is mixed (small to moderate), and the evidence base is limited to overweight and obese adults, with only one study providing dose and duration data (150 mg/day for 28 days). Overall, the findings are preliminary and inconsistent.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. The highest-quality study (RCT) found no significant effect, while a meta-analysis and a review suggest small-to-moderate benefits; however, this may reflect publication bias or heterogeneity. Only one study reported a dose (150 mg/day for 28 days), limiting dose extrapolation.
Postprandial changes in biomarkers were also comparable.
moderate-certainty evidence indicated that resveratrol supplementation may ... reduce inflammation
dampened inflammation