The effect of saffron supplementation on indices of oxidative stress, inflammation, mental health, and quality of life in patients with Parkinson's disease: a randomized, triple-blind, placebo-controlled clinical trial.
- 2026
- RCT · n = 92
- Food & function 17(2)
- Zahra Hajhashemy
- Mohammad Bagherniya
- Omid Sadeghi
- Fariborz Khorvash
- Gholamreza Askari
- PubMed: 41439298
- DOI: 10.1039/d5fo01924a
- High evidence
- Rigorous Journal
- Clinical
the saffron group in comparison with the placebo group showed marginal decreases in the values of malondialdehyde (adjusted mean difference: -0.32 nmol mL⁻¹ and 95% CI: -0.69, 0.03; P_ANCOVA = 0.07)
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 100 mg/day