Thistle and Reduced Antituberculosis Drug-Induced Liver Injury

• Prophylactic Therapy of Silymarin (Milk Thistle) on Antituberculosis Drug-Induced Liver Injury: A Meta-Analysis of Randomized Controlled Trials.

  • 2019-01-10
  • Meta-Analysis · n = 1,198
  • Canadian journal of gastroenterology & hepatology 2019
  • • Lina Tao
    • Xiaoyu Qu
    • Yue Zhang
    • Yanqing Song
    • Si-Xi Zhang

  • PubMed: 30733935
  • DOI: 10.1155/2019/3192351

  4 Insights on

  • Reduced Antituberculosis Drug-Induced Liver Injury

  • High evidence
  • Clinical

  Overall, silymarin significantly reduced the occurrence of anti-TB DILI at week 4 [RR: 0.33, 95% CI (0.15, 0.75)].

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes