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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Thistle and Reduced Hepatic Steatosis Grade

Doses used in studies

mg/day: 420 (median 420, IQR 420–420) — 1 study

Time to effect

Median: 9 weeks · IQR 9 weeks–9 weeks · Range 9 weeks–9 weeks — Reported in 1 of 1 study

1 of 1 paper

Evaluation of oral silymarin formulation efficacy in prevention of doxorubicin induced hepatotoxicity in patients with non-metastatic breast cancer.
- 2024-08-07
- RCT · n = 50
- Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 31(6)
- - Ashkan Fatemi Shandiz
  - Gholamreza Karimi
  - Mahdiyeh Dayyani
  - Sare Hosseini
  - Sepideh Elyasi
- PubMed: 39110237
- DOI: 10.1177/10781552241268778
3 Insights on
- Reduced Hepatic Steatosis Grade
- High evidence
- Clinical
Based on ultrasonography, the fatty liver grade was significantly higher in the placebo group at the end of the study.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
420 mg/day