A Randomized Controlled Trial to Determine the Effects of Curcumin and Epigallocatechin-3-Gallate Supplementation on Serum Brain-Derived Neurotrophic Factor and Mood Disturbance in Adults.
- 2026-03-06
- RCT
- Nutrients 18(5)
- Aidan M Cavanah
- Laura A Robinson
- Madison M Aguilar
- Elaine F Molaison
- Michael W Greene
- Michael D Roberts
- Andrew D Fruge
- PubMed: 41830024
- DOI: 10.3390/nu18050855
- High evidence
- Rigorous Journal
- Adults
Significant improvements were observed across all participants for mood (DASS-21 composite and subscales, GAD-7, p < 0.001 for all), with no significant difference between supplement and placebo groups.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No
- Dose
- 1330 mg/day