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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Turmeric and Reduced High-Sensitivity C-Reactive Protein Level

Doses used in studies

mg/day: 300–1,500 (median 900, IQR 600–1,200) — 2 studies

Time to effect

Median: 7.6 months · IQR 5.3 months–9.9 months · Range 3 months–12.2 months — Reported in 2 of 2 studies

2 of 2 papers

Curcumin Supplementation Reduces Inflammation, Neutrophil-to-Lymphocyte Ratio (NLR), and Antioxidant Status in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial.
- 2026-04-27
- RCT · n = 114
- International journal of molecular sciences 27(9)
- - Metha Yaikwawong
  - Khanittha Kamdee
  - Somlak Chuengsamarn
- PubMed: 42123439
- DOI: 10.3390/ijms27093854
8 Insights on
- Reduced High-Sensitivity C-Reactive Protein Level
- High evidence
- Large Human Trial
- Rigorous Journal
- Clinical
hs-CRP and NLR (p < 0.05)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
1500 mg/day
Efficacy and safety evaluation of Boswellia serrata and Curcuma longa extract combination in the management of chronic lower back pain: A randomised, double-blind, placebo-controlled clinical study.
- 2024-12-18
- RCT · n = 45
- Explore (New York, N.Y.) 21(1)
- - Anuradha Majumdar
  - Mungara Anjaneya Venkata Vara Prasad
  - Satish Reddy Gandavarapu
  - Kalakata Sudhir Kumar Reddy
  - Varun Sureja
  - Dharmeshkumar Kheni
  - Vishal Dubey
- PubMed: 39700654
- DOI: 10.1016/j.explore.2024.103099
9 Insights on
- Reduced High-Sensitivity C-Reactive Protein Level
- High evidence
- Clinical
This group demonstrated a significant reduction in inflammatory biomarker levels (...high-sensitivity C-reactive protein)
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
300 mg CL20192 once daily