Best Supplements for Reduced High-Sensitivity C-Reactive Protein Level
Ranked by research evidence. Compare 40 supplements across 50 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence4 studies
Across 4 studies, 2 reported beneficial moderate-sized effects on hs-CRP reduction, while 2 reported neutral small effects. The median study duration was 84 days (12 weeks). Doses varied widely (200 IU to 40,000 IU/week), with the most effective dose in beneficial studies being 2,000 IU/day.
Product matchViva Naturals — Vitamin D3 with Organic Liquid Coconut Oil125 mcg · $15.16 · ★5.0 (208) - Low evidence3 studies
Across 3 studies, 1 reported a beneficial moderate-sized effect on reducing high-sensitivity C-reactive protein (hs-CRP), while 2 found neutral (non-significant) small effects. The evidence base is small and preliminary, with the most-studied populations being clinical (obese patients and children on hemodialysis). Median study duration was 63 days (8-9 weeks), though effects were inconsistently observed.
- LowVitamin DAcross 4 studies, 2 reported beneficial moderate-sized effects on hs-CRP reduction, while 2 reported neutral small effects. The median study duration was 84 days (12 weeks). Doses varied widely (200 IU to 40,000 IU/week), with the most effective dose in beneficial studies being 2,000 IU/day.2 beneficial2 neutral4 studies
- LowL-CarnitineAcross 3 studies, 1 reported a beneficial moderate-sized effect on reducing high-sensitivity C-reactive protein (hs-CRP), while 2 found neutral (non-significant) small effects. The evidence base is small and preliminary, with the most-studied populations being clinical (obese patients and children on hemodialysis). Median study duration was 63 days (8-9 weeks), though effects were inconsistently observed.1 beneficial2 neutral3 studies