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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Best Supplements for Reduced High-Sensitivity C-Reactive Protein Level

Ranked by research evidence. Compare 36 supplements across 42 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.

Top picks by evidence

  • Low evidence4 studies

    Across 4 studies, evidence for vitamin D reducing hs-CRP is mixed: 2 studies reported beneficial effects (one moderate, one moderate effect size) and 2 reported neutral effects (both small). Statistically significant findings were limited to 2 studies. The most-studied dose was 2,000 IU/day, and effects were observed in clinical populations over a median duration of 84 days (12 weeks).

    Dose: 2,000 IU/day
    Product match
    Viva NaturalsVitamin D3 with Organic Liquid Coconut Oil
    125 mcg · $15.16 · ★5.0 (208)
36 supplements
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