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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Cardamom

What does the research say about Cardamom?

3 health outcomes synthesised

Cardamom has been researched across 3 health outcomes, with the strongest evidence supporting its effects on reducing interleukin-6 levels (3 studies, moderate evidence) and triglyceride levels (3 studies, moderate evidence). The most studied dose is 3 g/day, and research has primarily focused on populations with metabolic syndrome, PCOS, and non-alcoholic fatty liver disease.

Strongest evidence: Cardamom shows moderate evidence for reducing interleukin-6 levels and triglyceride levels, each supported by 3 studies with small effect sizes. For interleukin-6, 3 out of 3 studies reported beneficial effects, with a dose of 3 g/day over 120 days showing significant reductions in patients with metabolic syndrome and obese women with PCOS. For triglycerides, all 3 studies reported significant reductions, with a meta-analysis showing a mean reduction of -14.09 mg/dL, and the most specified dose was 3 g/day over 90 days in general adult and NAFLD populations.

Mixed or weaker evidence: Evidence for reducing blood cholesterol is weaker (low evidence strength), with only 1 out of 3 studies showing a small beneficial effect (reduction of -8.56 mg/dL in total cholesterol), while 2 studies found no significant effect. The beneficial result comes from a 2024 meta-analysis, while older studies (2020, 2019) were neutral, suggesting possible inconsistency or emerging evidence.

Effective dose patterns: Across outcomes, 3 g/day consistently appears as the most studied dose, particularly in trials lasting 90–120 days. The dose is primarily reported in capsule or powdered form, though specific formulations were not extracted from the studies.

Population insights: Research has focused on clinical populations — patients with metabolic syndrome and related disorders, obese women with PCOS, and overweight or obese NAFLD patients. No studies specifically highlight benefits in healthy or deficient populations.

Notable caveats: The evidence base across all outcomes is small (only 3 studies per outcome), so conclusions should be considered preliminary. The overwhelmingly positive direction of results raises concerns about publication bias (null-result studies may be unpublished or unindexed). Study designs, durations, and forms varied, and optimal dosing and long-term effects are not well established.

Frequently asked

  • What is Cardamom good for according to research?
    Research suggests cardamom may help reduce interleukin-6 levels and triglyceride levels, based on moderate evidence from 3 studies each. Evidence for reducing total cholesterol is weaker and mixed, with only 1 of 3 studies showing a benefit.
  • What dose of Cardamom is typically used in studies?
    The most studied dose is 3 g/day, typically administered over 90 to 120 days. This dose was used in trials for reducing interleukin-6, triglycerides, and cholesterol, primarily in clinical populations.
  • Who benefits most from Cardamom?
    Most studies have focused on clinical populations, including patients with metabolic syndrome, obese women with PCOS, and overweight or obese NAFLD patients. Research in healthy or general populations is limited.
  • Are there caveats or limitations in the research on Cardamom?
    Yes, the evidence base is small — only 3 studies per outcome — so findings should be considered preliminary. The consistently positive results may reflect publication bias, and optimal dosing, long-term effects, and specific formulations are not well established.
  • Does Cardamom help with reducing inflammation?
    There is moderate evidence that cardamom reduces interleukin-6 levels, an inflammatory marker, based on 3 studies all showing beneficial effects. Effects were small but consistent in clinical populations, with a dose of 3 g/day over 120 days showing significant reductions.
  • Does Cardamom help with lowering cholesterol?
    Evidence is weak and mixed. Only 1 of 3 studies showed a small reduction in total cholesterol, while 2 studies found no significant effect. The beneficial result comes from a single 2024 meta-analysis, while older studies were neutral.
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