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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus rhamnosus GG

Safety profile

7 studies reporting safety data1 serious adverse event

Across 7 clinical studies, no adverse events were found to be significantly increased with Lactobacillus rhamnosus GG compared to control. Two studies reported no significant difference in specific events (bacterial cholangitis and death), and 7 studies described the substance as generally well tolerated, though one flagged serious adverse events (deaths and liver transplants) that did not differ statistically from placebo. Overall, Lactobacillus rhamnosus GG was not associated with increased risk of adverse outcomes in the available trials.

Caveats: Most studies were small and not primarily designed to assess safety, so rare adverse events may not have been detected. The evidence base is limited to specific patient populations (e.g., children with biliary atresia, infants with cow's milk allergy), and long-term safety data are lacking.

Most-studied combinations with Lactobacillus rhamnosus GG

most supplement research is combination research
  • Oral Health Probiotics

    By NatureWise

    4.7 (642 reviews)
    Out of Stock
    Available From
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    Amazon
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    iHerb
    $31.54
    In
    Vitacost
    $26.99
    In
    Vitamin Shoppe
    $-
    Out
  • Available From
    Available From
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    Amazon
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    iHerb
    $19.19
    In
    Vitacost
    $19.69
    In
    Vitamin Shoppe
    $19.99
    In
  • Prenatal Probiotic

    By LoveBug Probiotics

    4.8 (678 reviews)
    Out of Stock
    Available From
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    Amazon
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    iHerb
    $24.95
    In
    Vitacost
    $-
    Out
    Vitamin Shoppe
    $-
    Out
  • Teen Clearface Vitamins

    By Codeage

    4.7 (402 reviews)
    Out of Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    Out
    iHerb
    $27.99
    In
    Vitacost
    $27.99
    In
    Vitamin Shoppe
    $27.99
    In
  • Probiotics

    By Culturelle

    4.6 (2.1K reviews)
    Out of Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
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    iHerb
    $25.65
    In
    Vitacost
    $22.29
    In
    Vitamin Shoppe
    $-
    Out
  • Fortify

    By Nature's Way

    4.6 (268 reviews)
    In Stock
    Available From
    Available From
    MerchantPriceStockAction
    Amazon
    $-
    Out
    iHerb
    $17.27
    In
    Vitacost
    $-
    Out
    Vitamin Shoppe
    $-
    Out
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