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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lactobacillus rhamnosus GG and Reduced Body Weight

Doses used in studies

CFU/day: 10 billion (median 10 billion, IQR 10 billion–10 billion) — 1 study

Time to effect

Median: 10 weeks · IQR 9 weeks–11 weeks · Range 8 weeks–2.8 months — Reported in 2 of 2 studies

2 of 2 papers

Lactobacillus GG is associated with mucin genes expressions in type 2 diabetes mellitus: a randomized, placebo-controlled trial.
- 2023-03-30
- RCT · n = 34
- European journal of nutrition 62(5)
- - Beyza Eliuz Tipici
  - Ender Coskunpinar
  - Derya Altunkanat
  - Penbe Cagatay
  - Beyhan Omer
  - Sukru Palanduz
  - Ilhan Satman
  - Ferihan Aral
- PubMed: 36997822
- DOI: 10.1007/s00394-023-03139-3
9 Insights on
- Reduced Body Weight
- High evidence
- Rigorous Journal
- Clinical
daily fat intake (p = 0.003), body weight (p = 0.014), and body fat (p = 0.015) in the probiotic group were significantly decreased.
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
10 × 10^9 Cfu/day
Effects of early postoperative synbiotic supplementation on gastrointestinal outcomes after sleeve gastrectomy: A randomized controlled trial.
- 2026-08
- RCT · n = 60
- Clinical nutrition (Edinburgh, Scotland) 63
- - Ayten Altunsaray
  - Birgül Dağ
  - Ayhan Dağ
- PubMed: 42400993
- DOI: 10.1016/j.clnu.2026.106717
5 Insights on
- Reduced Body Weight
- High evidence
- Clinical
While both groups showed significant reductions in body weight and body composition parameters over time, no significant between-group differences were detected.
Effect
Neutral
Effect size
Small
Significant
No