Best Supplements for Improved Gut Microbiota Composition
Ranked by research evidence. Compare 77 supplements across 110 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence6 studies
Across 3 studies, all reported beneficial effects on gut microbiota composition, with moderate effect sizes in two studies and a small effect in one. The only specified population was adults with alcoholic liver disease (ALD) in one study; doses and durations were not consistently reported.
- Low evidence5 studies
Across 3 studies, all reported beneficial effects on gut microbiota composition, with predominantly small effect sizes (two small, one moderate). Only one study reported statistical significance. The evidence is derived from animal, in vitro, and review studies; no human clinical trials are available.
- Low evidence4 studies
Across 3 studies (all beneficial), moderate to small effects were observed for improved gut microbiota composition with Lactobacillus rhamnosus. No consistent dose, population, or study duration was reported, and all studies were either reviews or an animal model. The evidence base is too limited to define a typical effect magnitude or applicable population.
- LowBifidobacterium plantarumAcross 3 studies, all reported beneficial effects on gut microbiota composition, with moderate effect sizes in two studies and a small effect in one. The only specified population was adults with alcoholic liver disease (ALD) in one study; doses and durations were not consistently reported.6 beneficial6 studies
- LowBifidobacterium animalis subsp. lactis BB-12Across 3 studies, all reported beneficial effects on gut microbiota composition, with predominantly small effect sizes (two small, one moderate). Only one study reported statistical significance. The evidence is derived from animal, in vitro, and review studies; no human clinical trials are available.5 beneficial5 studies
- LowLactobacillus rhamnosusAcross 3 studies (all beneficial), moderate to small effects were observed for improved gut microbiota composition with Lactobacillus rhamnosus. No consistent dose, population, or study duration was reported, and all studies were either reviews or an animal model. The evidence base is too limited to define a typical effect magnitude or applicable population.4 beneficial4 studies
- LowBifidobacterium bifidum Bb-02Across 3 studies, all reported beneficial effects on gut microbiota composition, with a predominant effect size of moderate. Evidence comes primarily from an animal model (mice with atopic dermatitis) and two reviews; no human clinical trials were identified. No consistent dose or duration data were reported across studies.3 beneficial3 studies