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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Lactobacillus rhamnosus and Improved Gut Microbiota Composition

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects on gut microbiota composition, with two showing moderate effect sizes and one showing a small effect. No consistent dose range, study duration, or form was reported across studies. The evidence base is small and preliminary.

  • Studied populations: high-fat diet-induced obese mice (from one study); otherwise, populations not specified

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the studies reported statistical significance, and all were review or animal-model studies, limiting applicability to human supplementation.

Generated Jun 11, 2026
4 of 4 papers
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