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Lactobacillus reuteri NCIMB 30242

What does the research say about Lactobacillus reuteri NCIMB 30242?

2 health outcomes synthesised

Lactobacillus reuteri NCIMB 30242 has been researched for 2 health outcomes, primarily in hypercholesterolemic adults. The strongest evidence is for reducing blood cholesterol, supported by 3 studies with moderate evidence strength, including a randomized controlled trial showing a 9.14% reduction in total cholesterol. Effective doses were not consistently reported across studies, limiting dose-specific conclusions.

Strongest evidence: Reduced blood cholesterol has moderate evidence strength from 3 studies, all reporting beneficial effects. The highest-quality trial in hypercholesterolemic adults (n=127) found a small effect size, with total cholesterol reduced by 9.14% (p<0.001). Effective dose ranges were not reported consistently.

Mixed or weaker evidence: Improved blood lipid profile has low evidence strength based on 3 studies. While all reported benefits, the strongest study showed only small reductions in LDL-C/HDL-C ratio (-13.39%) and apoB-100/apoA-1 ratio (-9.00%). Two of the three studies are lower-quality reviews lacking quantitative detail.

Effective dose patterns: No cross-cutting dose insights are available, as effective dose was not reported in either synthesis.

Population insights: All research was conducted in hypercholesterolemic adults, with no data on other populations such as children, elderly, or healthy individuals.

Notable caveats: The evidence base is very small (only 3 studies per outcome), and conclusions should be considered preliminary. Available studies are overwhelmingly positive, suggesting possible publication bias (null results less likely published). Study durations were not consistently reported, and two of three lipid profile studies are lower-quality reviews.

Frequently asked

  • What is Lactobacillus reuteri NCIMB 30242 good for according to research?
    Based on research, Lactobacillus reuteri NCIMB 30242 has been studied for two outcomes: reducing blood cholesterol and improving blood lipid profile, both in hypercholesterolemic adults. Three studies suggest it may reduce total cholesterol by about 9.14%, with moderate evidence strength.
  • What dose of Lactobacillus reuteri NCIMB 30242 is typically used in studies?
    Effective doses were not consistently reported across the studies in either synthesis. The available research does not provide a clear dose range for this probiotic strain.
  • Who benefits most from Lactobacillus reuteri NCIMB 30242?
    All research has been conducted in hypercholesterolemic adults. There is no evidence regarding its effects in other populations, such as children, the elderly, or individuals with normal cholesterol levels.
  • Are there caveats or limitations in the research on Lactobacillus reuteri NCIMB 30242?
    Yes, the evidence base is small (only 3 studies per outcome), making conclusions preliminary. The available studies are overwhelmingly positive, suggesting publication bias. Study durations were not consistently reported, and some studies were lower-quality reviews.
  • Does Lactobacillus reuteri NCIMB 30242 help with reducing blood cholesterol?
    Evidence is moderate for this outcome. All 3 studies reported beneficial effects, with the strongest trial showing a 9.14% reduction in total cholesterol. However, effect sizes were small, and the evidence base is limited.
  • Does Lactobacillus reuteri NCIMB 30242 improve blood lipid profile?
    Evidence is low for this outcome. While all 3 studies reported benefits, only one high-quality trial showed statistically significant reductions in LDL-C/HDL-C ratio (-13.39%) and apoB-100/apoA-1 ratio (-9.00%). The other two studies lacked quantitative detail.

Most-studied combinations with Lactobacillus reuteri NCIMB 30242

most supplement research is combination research
Also studied with:Lactobacillus fermentum CECT5716 (2)

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