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Evidence-Based Supplement Research
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Lactobacillus reuteri NCIMB 30242 and Improved Blood Lipid Profile

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects of Lactobacillus reuteri NCIMB 30242 on blood lipid profiles, with effect sizes ranging from small to moderate. The highest-quality evidence, a randomized controlled trial in hypercholesterolemic adults (n=127), showed a small but statistically significant reduction in LDL-C/HDL-C ratio (-13.39%) and apoB-100/apoA-1 ratio (-9.00%). The predominant effect size across studies is moderate, though the evidence base is small and preliminary.

  • Studied populations: Hypercholesterolemic adults

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Only one study reported a dose and demonstrated statistical significance; the two reviews lack quantitative detail and are lower quality.

Generated Jul 12, 2026
3 of 3 papers
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