Lactobacillus reuteri NCIMB 30242 and Improved Blood Lipid Profile

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects for improved blood lipid profile, with a predominant effect size of moderate. One high-quality RCT (n=127) found a small significant reduction in LDL-C/HDL-C ratio (13.39%, p=0.006) and apoB-100/apoA-1 (9.00%, p=0.026) in hypercholesterolemic adults. Two reviews reported moderate benefits, but these are based on the same RCT and lack independent data. Dose and duration were not consistently reported.

Studied populations: hypercholesterolemic adults

Caveats: The evidence is largely based on a single RCT from 2012 with a small effect size; the two reviews do not provide new independent data. No consistent dose or duration information is available, and the findings may not generalize to normocholesterolemic individuals.

Generated May 11, 2026

3 of 3 papers

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial
- 2012-09-19
- RCT · n = 127
- European Journal of Clinical Nutrition 66(11)
- - M. L. Jones
  - C. Martoni
  - S. Prakash
- PubMed: 22990854
- DOI: 10.1038/ejcn.2012.126
19 Insights on
- Improved Blood Lipid Profile
- High evidence
- Highly Cited
- Rigorous Journal
The ratios of LDL-C/HDL-cholesterol (HDL-C) and apoB-100/apoA-1 were reduced by 13.39% (P = 0.006) and 9.00% (P = 0.026), respectively, relative to placebo.
Effect
Beneficial
Effect size
Small
Significant
Yes
Encapsulation and Functional Activity of Lactobacillus reuteri Strains: Advances, Challenges, and Perspectives.
- 2026-02-24
- Review
- Comprehensive reviews in food science and food safety 25(2)
- - León-Espinosa Erika Berenice
  - Barrios-Francisco Rigoberto
  - Colin-Molina Abraham
  - Martínez-Palma Nikte Yoliztli
  - Rentería-Ortega Minerva
- PubMed: 41732827
- DOI: 10.1111/1541-4337.70412
4 Insights on
- Improved Blood Lipid Profile
- Low evidence
consumption of Lactobacillus reuteri NCIMB 30242 lowered total cholesterol and LDL-cholesterol, and raised HDL-cholesterol
Effect
Beneficial
Effect size
Moderate
Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis.
- 2025-07-01
- Review
- Frontiers in nutrition 12
- - Jiecheng Wei
  - Wenshuo Ding
  - Kaiyi Song
  - Yongkang Zhang
  - Qi Luo
  - Chan Qi
- PubMed: 40667443
- DOI: 10.3389/fnut.2025.1581971
1 Insight on
- Improved Blood Lipid Profile
- Low evidence
Consumption of Lactobacillus reuteri NCIMB 30242 has been associated with reductions in total cholesterol and LDL-cholesterol in human studies.
Effect
Beneficial
Effect size
Moderate

Lactobacillus reuteri NCIMB 30242 and Improved Blood Lipid Profile

Cholesterol lowering and inhibition of sterol absorption by Lactobacillus reuteri NCIMB 30242: a randomized controlled trial

Encapsulation and Functional Activity of Lactobacillus reuteri Strains: Advances, Challenges, and Perspectives.

Next-generation probiotics and engineered BEVs for precision therapeutics in osteoporosis.