Across 4 studies, all reported beneficial effects on reducing inflammatory markers, with 3 reaching statistical significance. The predominant effect size was small, though one systematic review (evidence score 4) reported a moderate effect. No consistent dose or form was reported across studies. The most specific population studied was adults who exercise regularly (athletes), but other studies did not specify a population segment.
Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Study durations were not consistently reported, limiting assessment of time-to-effect.
The available evidence suggests that curcumin is a safe medicinal agent that improves multiple clinical outcomes
from: Curcumin and multiple health outcomes: critical umbrella review of intervention meta-analyThe findings suggest that curcumin has potentially positive effects on ... inflammatory markers and oxidative stress
It also appears to have the capability to lower biomarkers associated with inflammation
Curcumin's anti-inflammatory properties are related to the inhibition of the NF-κB pathway, leading to the reduction in inflammatory markers in adipocytes and macrophages
curcumin reduces inflammatory markers (IL-8, TNF-α) in endometriosis