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Evidence-Based Supplement Research
Evidence-Based Supplement Research

Turmeric and Reduced Pain

Research synthesisHigh evidenceModerate effect14 studies · 9 beneficial · 5 neutral · 0 harmful

Across 14 studies, 9 reported beneficial effects of turmeric/curcumin on pain reduction, with 5 studies finding no significant benefit (neutral). The predominant effect size was moderate. Evidence comes primarily from clinical populations with osteoarthritis, rheumatoid arthritis, chronic lower back pain, and oral inflammatory conditions, with a median study duration of 90 days suggesting benefits are observed with longer-term use. Doses varied widely, but when reported, ranged from 170 mg to 600 mg per day of curcuminoid extracts, often in combination with other agents.

  • Studied populations: People with osteoarthritis (knee, hand), rheumatoid arthritis, chronic lower back pain, and oral inflammatory conditions such as recurrent aphthous stomatitis and oral lichen planus.

Caveats: Many studies used combination formulations (e.g., with Boswellia serrata, vitamins) or different curcuminoid extracts, complicating isolation of turmeric's specific effect. Evidence is primarily from trials lasting 90 days or longer; short-term effects are less documented. Some neutral results were observed in conditions like hand osteoarthritis and oral lichen planus, suggesting variability by condition and formulation. The available evidence is largely positive but includes several neutral findings, indicating that turmeric may not be effective for all pain types.

Generated Jul 17, 2026
Doses used in studies
  • mg/day: 170–1,200 (median 300, IQR 235750) 3 studies
Time to effect
Median: 3 months · IQR 10.7 weeks3 months · Range 8.6 weeks3 months — Reported in 3 of 14 studies
Safety in these studies
14 of 14 papers
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