Research synthesisModerate evidenceModerate effect4 studies · 3 beneficial · 1 neutral · 0 harmful
Across 4 studies, 3 reported beneficial effects on reducing pro-inflammatory cytokine levels, with effect sizes ranging from moderate to large; one neutral study found a small non-significant effect. The most robust evidence comes from a 12-month RCT in 114 adults with type 2 diabetes using 1500 mg/day curcumin, showing large significant reductions. Most studies focused on clinical populations with metabolic conditions (e.g., type 2 diabetes, NAFLD, metabolic syndrome), but two systematic reviews included turmeric among mixed polyphenol interventions, limiting attribution.
- Studied populations: adults with metabolic conditions (type 2 diabetes, non-alcoholic fatty liver disease, metabolic syndrome, obesity)
Caveats: Only one study (RCT) tested turmeric (curcumin) at a specific dose (1500 mg/day) and duration (365 days); other studies were systematic reviews that combined turmeric with other polyphenols, making it difficult to isolate its effect. The neutral systematic review (evidence score 7) suggests variability in results. Evidence base is small (4 studies) and conclusions should be considered preliminary.
Generated Jun 10, 2026