Skip to main content

Evidence-Based Supplement Research

Evidence-Based Supplement Research

Selenium and Reduced Anti-Thyroid Peroxidase Antibody Level

Doses used in studies

mcg/day: 200 (median 200, IQR 200–200) — 1 study

Time to effect

Median: 8.6 weeks · IQR 8.6 weeks–8.6 weeks · Range 8.6 weeks–8.6 weeks — Reported in 1 of 2 studies

2 of 2 papersPopulation:

Effect of Selenomethionine- Enriched Yeast on Hypothyroidism Patients.
- 2025-02-01
- RCT · n = 40
- Archives of Razi Institute 80(1)
- - A Hajyasini
  - A Dehnad
  - A Farzi
  - M Mobasseri
  - A Ostadrahimi
  - B Kafili
- PubMed: 40951555
- DOI: 10.32592/ari.2025.80.1.257
7 Insights on
- Reduced Anti-Thyroid Peroxidase Antibody Level
- High evidence
- Clinical
TSH and anti-TPO levels exhibited a relative decrease in the intervention group (P>0.05).
Effect
Neutral
Effect size
Small
Significant
No
Dose
200 µg/day for 60 days
Selenium and thyroid diseases.
- 2023-03-24
- Review
- Frontiers in endocrinology 14
- - Fei Wang
  - Chunyu Li
  - Shaoxin Li
  - Lili Cui
  - Junyu Zhao
  - Lin Liao
- PubMed: 37033262
- DOI: 10.3389/fendo.2023.1133000
4 Insights on
- Reduced Anti-Thyroid Peroxidase Antibody Level
- Low evidence
Selenium supplementation in Hashimoto's thyroiditis was associated with the decreased levels of anti-thyroid peroxidase antibody and improved thyroid ultrasound structure.
Effect
Beneficial
Effect size
Small
Significant
Yes