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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Zinc and Increased Total Testosterone Level

Doses used in studies

mg/day: 10 (median 10, IQR 10–10) — 1 study

Time to effect

Median: 3 months · IQR 3 months–3 months · Range 3 months–3 months — Reported in 1 of 1 study

1 of 1 paper

Evaluation of in vivo supplementation of 2660 mg D-aspartic acid and 200 mg ubiquinol and 10 mg zinc on different semen parameters in idiopathic male infertility: a randomized double blind placebo controlled study.
- 2025-04-18
- RCT · n = 75
- Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 97(2)
- - Sameh Fayek GamalEl Din
  - Elnashar A M
  - Yasser Elkhiat
  - Tarek Hussein
  - Mohamed Ahmed AbdElSalam
  - Ayman Alam
  - David Ramzy
  - Islam Moatamed
  - Ashraf Zeidan
  - Amr Elahwany
  - Mohamed Wael Ragab
  - Omar Zahran
  - Hany Saad
- PubMed: 40248985
- DOI: 10.4081/aiua.2025.13554
2 Insights on
- Increased Total Testosterone Level
- High evidence
- Clinical
Also, they showed highly significant increase in total testosterone level (5.06 ± 1.74 vs 5.89 ± 1.62, p=0.009).
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
10 mg/day