Zinc and Reduced Pain

• Time-dependent efficacy of zinc supplements in preventing oral mucositis after chemoradiotherapy: a meta-analysis.

  • 2026-03-24
  • Meta-Analysis · n = 1,076
  • Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 34(4)
  • • Jiale Wang
    • Jianyu Hu
    • Yongshi Luo
    • Jinfeng Nie
    • Mangui Deng
    • Zhihong Wang

  • PubMed: 41872524
  • DOI: 10.1007/s00520-026-10572-7

  5 Insights on

  • Reduced Pain

  • High evidence

  zinc supplementation significantly alleviated pain scores at 3 and 6 weeks of treatment (MD = -1.82 and -2.02, respectively).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  not specified in aggregate