Bacillus amyloliquefaciens and Reduced Infection Severity

• In vitro and in vivo evaluation of Bacillus amyloliquefaciens E35 as prophylactic agents against Singapore grouper iridovirus.

  • 2026-07
  • Clinical Trial
  • Fish & shellfish immunology 174
  • • Yanxia Gao
    • Lingling Deng
    • Yibing Wang
    • Lin Huang
    • Jieying Yu
    • Xiangmou Qin
    • Junxiang Lai
    • Ermeng Yu
    • Shuyuan Zhang
    • Ying Pan
    • Jiwei Xu
    • Qing Yu
    • Pengfei Li

  • PubMed: 41941900
  • DOI: 10.1016/j.fsi.2026.111318

  2 Insights on

  • Reduced Infection Severity

  • Moderate evidence

  dietary supplementation with live E35 in T. ovatus led to significantly lower viral loads in liver, spleen, and head kidney, and reduced cumulative mortality, highlighting its potential to enhance host resistance against SGIV challenge

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes