Secondary Metabolites from Bacillus spp. probiotics as potential treatments for multidrug-resistant pathogens: A comprehensive review.
- 2025-05-09
- Review
- Current research in microbial sciences 8
- George Michael Nicolas
- PubMed: 40337641
- DOI: 10.1016/j.crmicr.2025.100392
- Low evidence
Spore-forming probiotics from Bacillus spp. show great interest as antimicrobial agents through the production of strain-specific bioactive secondary metabolites. This review summarizes the broad-spectrum antimicrobial activities of Bacillus spp. secondary metabolite groups and their reported mechanisms of action, underscoring the urgency in developing novel antimicrobial drugs.
- Effect
- Beneficial
- Effect size
- Moderate