Bacillus clausii and Improved Bowel Movement Frequency

• Efficacy of Bacillus clausii in Pediatric Functional Constipation: A Pilot of a Randomized, Double-Blind, Placebo-Controlled Trial.

  • 2023-02-09
  • RCT · n = 38
  • Indian pediatrics 60(6)
  • • Ponlakit Lojanatorn
    • Jirachart Phrommas
    • Pornthep Tanpowpong
    • Songpon Getsuwan
    • Chatmanee Lertudomphonwanit
    • Suporn Treepongkaruna

  • PubMed: 36757002
  • DOI: 10.1007/s13312-023-2907-0

  5 Insights on

  • Improved Bowel Movement Frequency

  • High evidence
  • Children

  Significant increases in the treatment success rate (22% to 56%, P=0.01) and mean stool frequency per week [3 (0.9) to 4.2 (1.7), P=0.01] were pronounced only in the placebo group.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  once daily for four weeks