Efficacy and Safety of Bacillus coagulans LBSC in Drug Induced Constipation Associated With Functional Gastrointestinal Disorder: A Double-Blind, Randomized, Interventional, Parallel, Controlled Trial a Clinical Study on Bacillus coagulans LBSC for Drug Induced Constipation Associated With FGIDs.

2024-01
RCT · n = 168
Global advances in integrative medicine and health 13
- Ankit Rathi
- Ravikiran Pagare

PubMed: 39295947
DOI: 10.1177/27536130241286511

Improved Constipation

High evidence

There was a significant reduction in occurrence of constipation (≥98.6% and P-value <0.05) in test arm over the placebo arm... significant improvements in degree of stool consistency... borderline significantly superior in degree of stool expulsion... significant reduction in scores for occurrence of constipation and degree of constipation... significant improvement in the scores for degree of stool consistency and degree of stool expulsion

Effect: Beneficial
Effect size: Moderate
Significant: Yes

Bacillus coagulans SNZ-1969 and Improved Constipation

Efficacy and Safety of Bacillus coagulans LBSC in Drug Induced Constipation Associated With Functional Gastrointestinal Disorder: A Double-Blind, Randomized, Interventional, Parallel, Controlled Trial a Clinical Study on Bacillus coagulans LBSC for Drug Induced Constipation Associated With FGIDs.

Spore-forming Bacillus coagulans SNZ 1969 improved intestinal motility and constipation perception mediated by microbial alterations in healthy adults with mild intermittent constipation: A randomized controlled trial.