Oral health benefits of Heyndrickxia coagulans: a systematic review and meta-analysis of current evidence.
- 2026-01-20
- Review · n = 183
- Frontiers in oral health 6
- Silvia Cirio
- Guglielmo Campus
- Claudia Salerno
- Aesha Allam
- Maria Grazia Cagetti
- PubMed: 41641154
- DOI: 10.3389/froh.2025.1733955
- High evidence
Administration of H. coagulans, via chewable tablets, mouthwash, or food matrices, resulted in a significant reduction of salivary S. mutans counts in both children and adults compared with placebo or other probiotics. Meta-analysis of four studies demonstrated a pooled effect size of -0.99...
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes