Does symbiotic supplementation which contains Bacillus Coagulans Lactobacillus rhamnosus, Lactobacillus acidophilus and fructooligosaccharide has favourite effects in patients with type-2 diabetes? A randomised, double-blind, placebo-controlled trial.
- 2021-06-02
- RCT · n = 50
- Archives of physiology and biochemistry 129(6)
- Aynaz Velayati
- Iman Kareem
- Meghdad Sedaghat
- Golbon Sohrab
- Omid Nikpayam
- Mehdi Hedayati
- Khadijeh Abhari
- Ehsan Hejazi
- PubMed: 34077686
- DOI: 10.1080/13813455.2021.1928225
- High evidence
- Clinical
Analysis of covariance demonstrated that fasting blood glucose (FBG), insulin, homeostatic Model Assessment for Insulin Resistance (HOMA-IR), β-cell function (HOMA-β) (p <.05) and hs-CRP (p <.05) significantly declined in the treatment group compared with the placebo group.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- one sachet daily for 12 weeks