Effects of spore-forming probiotic Bacillus subtilis HU58™ in children with antibiotic-associated diarrhoea: a randomised, double-blind, placebo-controlled trial.
- 2025-07-25
- RCT · n = 68
- Beneficial microbes 17(1)
- K Sorensen
- P Jog
- S Mankar
- C Holz
- S Jadhav
- PubMed: 40716758
- DOI: 10.1163/18762891-bja00086
- High evidence
- Rigorous Journal
Greater improvements for both adapted GIRQ and PGA scores assessing GI wellbeing were observed in the probiotic group compared to the placebo group at days 3 and 7 (all P < 0.001).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes