Best Supplements for Improved Gastrointestinal Health
Ranked by research evidence. Compare 41 supplements across 68 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence7 studies
All 7 reviewed studies reported beneficial effects of kefir culture on gastrointestinal health, with effect sizes ranging from small to moderate. No statistically significant findings were reported across the included studies. The evidence base consists entirely of review articles, with no primary clinical trials, and no consistent dose or population data are available.
- Low evidence3 studies
Across 3 studies (all reviews), all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. The evidence comes entirely from review articles, with no extractable data on dose, duration, sample size, or statistical significance, and no original RCTs were identified.
- Low evidence3 studies
Across 3 review studies, all 3 report beneficial moderate-sized effects of *Bacillus clausii* SC-109 on gastrointestinal health. Evidence suggests improvements in intestinal microflora balance and reduced gastrointestinal discomfort, though no specific dose, duration, or population data are available from these studies.
- Very lowLactobacillus salivarius UCC118Across 10 studies, all reported beneficial effects of Lactobacillus salivarius UCC118 on gastrointestinal health, with effect sizes ranging from small to moderate. The majority of studies (6 of 10) reported small effects, while 3 reported moderate effects and 1 did not specify an effect size. All studies were review articles or non-clinical reports; no human trials with statistical significance were identified. No consistent dose range, form, or study duration was reported across the studies.10 beneficial10 studies
- LowKefir CultureAll 7 reviewed studies reported beneficial effects of kefir culture on gastrointestinal health, with effect sizes ranging from small to moderate. No statistically significant findings were reported across the included studies. The evidence base consists entirely of review articles, with no primary clinical trials, and no consistent dose or population data are available.7 beneficial7 studies
- LowLactobacillus rhamnosusAcross 3 studies (all reviews), all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. The evidence comes entirely from review articles, with no extractable data on dose, duration, sample size, or statistical significance, and no original RCTs were identified.3 beneficial3 studies
- LowBacillus clausii SC-109Across 3 review studies, all 3 report beneficial moderate-sized effects of *Bacillus clausii* SC-109 on gastrointestinal health. Evidence suggests improvements in intestinal microflora balance and reduced gastrointestinal discomfort, though no specific dose, duration, or population data are available from these studies.3 beneficial3 studies
- Very lowBifidobacterium plantarumAcross 3 studies, all reported beneficial but small effects for improved gastrointestinal health with Bifidobacterium plantarum. No doses, forms, or durations were consistently reported, and none of the included studies reached statistical significance. The evidence base is too limited to draw firm conclusions.3 beneficial3 studies
- Very lowBifidobacterium animalis subsp. lactis BB-12Across 3 studies, all reported beneficial effects on gastrointestinal health, with effect sizes ranging from small to large (predominantly moderate). The evidence is derived entirely from narrative reviews, with no specific dose, duration, or population data reported. Effect sizes were mixed (small to large) across the available studies.3 beneficial3 studies