Best Supplements for Improved Gastrointestinal Health
Ranked by research evidence. Compare 40 supplements across 67 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Low evidence7 studies
Across 7 review studies, all 7 reported beneficial effects of kefir culture on gastrointestinal health, with effect sizes ranging from small to moderate. No statistically significant findings were reported, and the most-studied dose range and specific populations were not consistently identified across the studies.
- Very low evidence10 studies
Across 10 studies, all reported beneficial effects on gastrointestinal health for Lactobacillus salivarius UCC118, but none achieved statistical significance. The predominant effect size was small, with a minority of reviews reporting moderate effects. No specific dose or population was consistently studied, and the evidence base consists entirely of narrative reviews and non-human studies.
- Very low evidence3 studies
Across 3 studies, all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. However, none of the findings were statistically significant, and evidence is drawn exclusively from review articles or non-clinical characterization studies without direct human trials. No consistent dose range or general population was identified.
- Very lowLactobacillus salivarius UCC118Across 10 studies, all reported beneficial effects on gastrointestinal health for Lactobacillus salivarius UCC118, but none achieved statistical significance. The predominant effect size was small, with a minority of reviews reporting moderate effects. No specific dose or population was consistently studied, and the evidence base consists entirely of narrative reviews and non-human studies.10 beneficial10 studies
- LowKefir CultureAcross 7 review studies, all 7 reported beneficial effects of kefir culture on gastrointestinal health, with effect sizes ranging from small to moderate. No statistically significant findings were reported, and the most-studied dose range and specific populations were not consistently identified across the studies.7 beneficial7 studies
- Very lowLactobacillus rhamnosusAcross 3 studies, all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. However, none of the findings were statistically significant, and evidence is drawn exclusively from review articles or non-clinical characterization studies without direct human trials. No consistent dose range or general population was identified.3 beneficial3 studies
- Very lowBifidobacterium plantarumAcross 3 studies, all reported beneficial effects of Bifidobacterium plantarum on gastrointestinal health, but effect sizes were uniformly small. No study reported statistically significant findings, and data on dose, duration, form, and population were largely absent. The evidence base is currently sparse and descriptive, limiting confidence in the observed benefit.3 beneficial3 studies
- Very lowBacillus clausii SC-109Across 3 review articles, all 3 reported moderate beneficial effects of Bacillus clausii SC-109 on gastrointestinal health. However, no dose, duration, or statistical significance data were provided, and one study was conducted in domestic cats, limiting generalizability to humans.3 beneficial3 studies
- Very lowBifidobacterium animalis subsp. lactis BB-12Across 3 review studies, all reported beneficial effects of Bifidobacterium animalis subsp. lactis BB-12 on gastrointestinal health, with effect sizes ranging from small to large (mixed). No statistically significant individual findings were available. Evidence is derived exclusively from review articles, and no specific dose, form, or population data were reported.3 beneficial3 studies