Lactobacillus rhamnosus and Improved Gastrointestinal Health

Research synthesisVery low evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. The evidence base is very small and preliminary, with no studies providing statistical significance data. Most formulations, doses, and study durations were not reported.

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the included studies reported statistical significance, and effect size estimates are based on qualitative descriptions from review abstracts rather than quantitative data.

Generated Jun 11, 2026

3 of 3 papers

Advancements in Microbial Applications for Sustainable Food Production.
- 2025-10-05
- Review
- Foods (Basel, Switzerland) 14(19)
- - Alane Beatriz Vermelho
  - Verônica da Silva Cardoso
  - Levy Tenório Sousa Domingos
  - Ingrid Teixeira Akamine
  - Bright Amenu
  - Bernard Kwaku Osei
  - Athayde Neves Junior
- PubMed: 41097595
- DOI: 10.3390/foods14193427
1 Insight on
- Improved Gastrointestinal Health
- Low evidence
Lactobacillus rhamnosus lysate powder was associated with improved bowel function and reduced gastrointestinal discomfort in the study abstract.
Effect
Beneficial
Effect size
Moderate
Overall Rebalancing of Gut Microbiota Is Key to Autism Intervention.
- 2022-05-26
- Review
- Frontiers in psychology 13
- - Chang Lu
  - Jiaqi Rong
  - Changxing Fu
  - Wenshi Wang
  - Jing Xu
  - Xing-Da Ju
- PubMed: 35712154
- DOI: 10.3389/fpsyg.2022.862719
5 Insights on
- Improved Gastrointestinal Health
- Low evidence
many studies have found that children with ASD are associated with gastrointestinal diseases, and the composition of intestinal microbiota (GM) is different from that of typical developing children
Effect
Beneficial
Effect size
Moderate
Characterization of the Probiotic Potential of Lactic Acid Bacteria Isolated from Kimchi, Yogurt, and Baby Feces in Hong Kong and Their Performance in Soymilk Fermentation.
- 2021-12-09
- Microorganisms 9(12)
- - Haicui Wu
  - Tim-Fat Shum
  - Jiachi Chiou
- PubMed: 34946146
- DOI: 10.3390/microorganisms9122544
4 Insights on
- Improved Gastrointestinal Health
- Low evidence
L. rhamnosus AC1 exhibited higher tolerance to acid, NaCl, bile salts, and phenol as compared to the other isolates tested... exhibited superior performance in soymilk fermentation and potential as a starter and probiotic culture.
Effect
Beneficial
Effect size
Moderate

Lactobacillus rhamnosus and Improved Gastrointestinal Health

Advancements in Microbial Applications for Sustainable Food Production.

Overall Rebalancing of Gut Microbiota Is Key to Autism Intervention.

Characterization of the Probiotic Potential of Lactic Acid Bacteria Isolated from Kimchi, Yogurt, and Baby Feces in Hong Kong and Their Performance in Soymilk Fermentation.