Lactobacillus rhamnosus and Improved Gastrointestinal Health

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies (all reviews), all reported beneficial moderate-sized effects of Lactobacillus rhamnosus on gastrointestinal health. The evidence comes entirely from review articles, with no extractable data on dose, duration, sample size, or statistical significance, and no original RCTs were identified.

Studied populations: children with ASD (one review), general population implied in another review

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. All studies are review articles (not original trials), with no reported doses, durations, sample sizes, or statistical significance values. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). No original RCTs or controlled studies were included in the database for this pair.

Generated May 12, 2026

3 of 3 papers

Advancements in Microbial Applications for Sustainable Food Production.
- 2025-10-05
- Review
- Foods (Basel, Switzerland) 14(19)
- - Alane Beatriz Vermelho
  - Verônica da Silva Cardoso
  - Levy Tenório Sousa Domingos
  - Ingrid Teixeira Akamine
  - Bright Amenu
  - Bernard Kwaku Osei
  - Athayde Neves Junior
- PubMed: 41097595
- DOI: 10.3390/foods14193427
1 Insight on
- Improved Gastrointestinal Health
- Low evidence
Lactobacillus rhamnosus lysate powder was associated with improved bowel function and reduced gastrointestinal discomfort in the study abstract.
Effect
Beneficial
Effect size
Moderate
Overall Rebalancing of Gut Microbiota Is Key to Autism Intervention.
- 2022-05-26
- Review
- Frontiers in psychology 13
- - Chang Lu
  - Jiaqi Rong
  - Changxing Fu
  - Wenshi Wang
  - Jing Xu
  - Xing-Da Ju
- PubMed: 35712154
- DOI: 10.3389/fpsyg.2022.862719
5 Insights on
- Improved Gastrointestinal Health
- Low evidence
many studies have found that children with ASD are associated with gastrointestinal diseases, and the composition of intestinal microbiota (GM) is different from that of typical developing children
Effect
Beneficial
Effect size
Moderate
Characterization of the Probiotic Potential of Lactic Acid Bacteria Isolated from Kimchi, Yogurt, and Baby Feces in Hong Kong and Their Performance in Soymilk Fermentation.
- 2021-12-09
- Microorganisms 9(12)
- - Haicui Wu
  - Tim-Fat Shum
  - Jiachi Chiou
- PubMed: 34946146
- DOI: 10.3390/microorganisms9122544
4 Insights on
- Improved Gastrointestinal Health
- Low evidence
L. rhamnosus AC1 exhibited higher tolerance to acid, NaCl, bile salts, and phenol as compared to the other isolates tested... exhibited superior performance in soymilk fermentation and potential as a starter and probiotic culture.
Effect
Beneficial
Effect size
Moderate

Lactobacillus rhamnosus and Improved Gastrointestinal Health

Advancements in Microbial Applications for Sustainable Food Production.

Overall Rebalancing of Gut Microbiota Is Key to Autism Intervention.

Characterization of the Probiotic Potential of Lactic Acid Bacteria Isolated from Kimchi, Yogurt, and Baby Feces in Hong Kong and Their Performance in Soymilk Fermentation.