Bifidobacterium animalis subsp. lactis BB-12 and Reduced Diarrhea Incidence

• Restitution of gut microbiota in Ugandan children administered with probiotics (Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12) during treatment for severe acute malnutrition.

  • 2020-01-20
  • RCT
  • Gut microbes 11(4)
  • • Josué L Castro-Mejía
    • Sinéad O'Ferrall
    • Łukasz Krych
    • Elaine O'Mahony
    • Hanifa Namusoke
    • Betty Lanyero
    • Witold Kot
    • Nicolette Nabukeera-Barungi
    • Kim Fleischer Michaelsen
    • Christian Mølgaard
    • Henrik Friis
    • Benedikte Grenov
    • Dennis S Nielsen

  • PubMed: 31959047
  • DOI: 10.1080/19490976.2020.1712982

  2 Insights on

  • Reduced Diarrhea Incidence

  • High evidence

  Children where the probiotic species were detected had lower cumulative incidence (p < .001) of diarrhea during the follow-up period compared to children receiving placebo and children receiving probiotics, but where the probiotics were not detected.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Probiotics: A multifaceted approach to health promotion-from disease prevention to food enrichment and delivery systems.

  • 2025-10-13
  • Review
  • AIMS microbiology 11(3)
  • • Srirengaraj Vijayaram
    • Vivekanandan K E
    • Sabariswaran Kandasamy
    • Hary Razafindralambo
    • Einar Ringø
    • Yun-Zhang Sun
    • Gayathri Kaliyannan

  • PubMed: 41078550
  • DOI: 10.3934/microbiol.2025026

  10 Insights on

  • Reduced Diarrhea Incidence

  • Low evidence

  Bifidobacterium animalis subsp. lactis BB-12 has been shown to reduce the incidence of diarrhea in healthy adults and children.

  Effect

  Beneficial

  Effect size

  Small