Probiotics: A multifaceted approach to health promotion-from disease prevention to food enrichment and delivery systems.
- 2025
- AIMS microbiology 11(3)
- Srirengaraj Vijayaram
- Vivekanandan K E
- Sabariswaran Kandasamy
- Hary Razafindralambo
- Einar Ringø
- Yun-Zhang Sun
- Gayathri Kaliyannan
- PubMed: 41078550
- DOI: 10.3934/microbiol.2025026
Probiotics are living microbes that impart overall health benefits when introduced appropriately. They play important roles in activating the immune system, inhibiting pathogens, balancing gut microbiota, providing relief from inflammatory diseases, and helping prevent chronic conditions such as cancer. In this manuscript, we address the multifaceted uses of probiotics in medicinal, food, and cosmetic industries, emphasizing new encapsulation techniques that improve their stability and effectiveness. Demonstrating their uses in food enrichment, disease prevention, and delivery systems, the manuscript offers valuable recommendations for the use of probiotics in different fields. It also anticipates future directions, such as the invention of new encapsulation techniques, the use of probiotics as personalized nutrition, and the application of their therapeutic benefits to new areas such as metabolic and neurodegenerative diseases. The paper demonstrates the potential of probiotics as promising candidates for the promotion of animal and human health in the modern era.
Research Insights
| Supplement | Health Outcome | Effect Type | Effect Size |
|---|---|---|---|
| Bifidobacterium animalis subsp. lactis BB-12 | Improved Gut Microbiota Balance | Beneficial | Moderate |
| Bifidobacterium animalis subsp. lactis BB-12 | Improved Immune Function | Beneficial | Small |
| Bifidobacterium animalis subsp. lactis BB-12 | Reduced Diarrhea Incidence | Beneficial | Small |
| Bifidobacterium animalis subsp. lactis BB-12 | Reduced Inflammation | Beneficial | Small |
| Bifidobacterium animalis subsp. lactis BB-12 | Reduced Pathogen Activity | Beneficial | Small |
| Bifidobacterium bifidum Bb-02 | Improved Gut Microbiota Balance | Beneficial | Moderate |
| Bifidobacterium bifidum/lactis Bb-02 | Improved Gut Microbiota Balance | Beneficial | Moderate |
| Bifidobacterium bifidum/lactis Bb-02 | Improved Immune Function | Beneficial | Small |
| Bifidobacterium plantarum | Improved General Health | Beneficial | Moderate |
| Bifidobacterium plantarum | Improved Overall Health | Beneficial | Small |
| Lactobacillus salivarius UCC118 | Improved Gastrointestinal Health | Beneficial | Small |