Bifidobacterium animalis subsp. lactis BB-12 and Reduced Inflammation

• Microbial modulators of the epigenome: probiotic regulation of MiRNAs and LncRNAs in health and disease and preventive medicine.

  • 2026-01-07
  • Review
  • Gut pathogens 18(1)
  • • Shanshan Xie
    • Yong Zhi
    • Bita Badehnoosh

  • PubMed: 41495822
  • DOI: 10.1186/s13099-025-00789-y

  3 Insights on

  • Reduced Inflammation

  • Low evidence

  These regulatory RNAs are essential mediators of gene silencing, chromatin remodeling, and cellular signaling pathways implicated in immunity, inflammation, cancer, and neurodegenerative diseases.

  Effect

  Beneficial

  Effect size

  Moderate

• Health benefits of Bifidobacterium animalis subsp. lactis BB-12 in infants and children: a mini-review.

  • 2026-02-19
  • Review
  • Frontiers in microbiology 17
  • • Carlos Patricio Acosta Rodríguez Bueno
    • Ailim Carias Domínguez
    • Denis Guyonnet
    • Etienne Pouteau

  • PubMed: 41800422
  • DOI: 10.3389/fmicb.2026.1773473

  8 Insights on

  • Reduced Inflammation

  • Low evidence

  Bifidobacteria-dominance in infancy is considered protective as they not only display both anti-inflammatory and immunomodulatory effects

  Effect

  Beneficial

  Effect size

  Small

• Probiotics: A multifaceted approach to health promotion-from disease prevention to food enrichment and delivery systems.

  • 2025-10-13
  • Review
  • AIMS microbiology 11(3)
  • • Srirengaraj Vijayaram
    • Vivekanandan K E
    • Sabariswaran Kandasamy
    • Hary Razafindralambo
    • Einar Ringø
    • Yun-Zhang Sun
    • Gayathri Kaliyannan

  • PubMed: 41078550
  • DOI: 10.3934/microbiol.2025026

  10 Insights on

  • Reduced Inflammation

  • Low evidence

  Bifidobacterium animalis subsp. lactis BB-12... providing relief from inflammatory diseases

  Effect

  Beneficial

  Effect size

  Small

• The Administration Matrix Modifies the Beneficial Properties of a Probiotic Mix of Bifidobacterium animalis subsp. lactis BB-12 and Lactobacillus acidophilus LA-5.

  • 2020-08-26
  • Probiotics and antimicrobial proteins 13(2)
  • • Gréta Pápai
    • Edgar Torres-Maravilla
    • Florian Chain
    • Éva Varga-Visi
    • Otília Antal
    • Zoltán Naár
    • Luis G Bermúdez-Humarán
    • Philippe Langella
    • Rebeca Martín

  • PubMed: 32851584
  • DOI: 10.1007/s12602-020-09702-2

  6 Insights on

  • Reduced Inflammation

  • Low evidence
  • Rigorous Journal

  Both probiotic candidates suppress the secretion of IL-8 secretion by HT-29-TNF-α stimulated cells.

  Effect

  Beneficial

  Effect size

  Small